炔诺酮联合宫腔镜子宫内膜息肉切除术治疗子宫内膜息肉的临床分析

The Clinical Analysis of Norethindrone Combined Hysteroscopic Endometrial Polyps Resection in the Treatment of Uterine Endometrial Polyps

目的：分析宫腔镜下子宫内膜息肉切除术（TCRP）联合炔诺酮治疗子宫内膜息肉（EP）的临床疗效,为EP治疗提供依据。方法：按照随机数字表法将80例子宫内膜息肉患者分为观察组和对照组各40例。对照组采用TCRP治疗,观察组在TCRP治疗后连续服用炔诺酮3个月,每次30-40 mg,每8小时服一次,共22 d/月。所有患者随访1年,比较两组月经改善率和子宫内膜息肉复发率。结果：随访1年,观察组月经正常37例（92.5%）、复发1例（2.5%）。观察组月经改善率和EP复发率与对照组比较差异均有统计学意义（字2=7.924、8.126,P〈0.05）。结论：TCRP联合炔诺酮治疗子宫内膜息肉可以明显改善因子宫内膜息肉所致的月经紊乱,同时有效降低子宫内膜息肉复发,是治疗子宫内膜息肉较为理想的治疗方法。

Objective：To analyze the clinical curative effect of endometrial polyps resection（TCRP）combined Norethisterone on endometrial polyps（EP）,in order to provide the basis for the treatment of EP. Method：80 cases of endometrial polyp were divided into observation group and control group with 40 cases in each according to random digit tablet. The control group was treated with TCRP therapy,while the observation group was treated with Norethisterone for 3 months after TCRP treatment,each time 30-40 mg,3 times a day,22 days/month.All patients were followed up for one year to compare the menstrual improvement rate and recurrence rate.Result：Follow up 1 year,the normal menstruation of observation group was 37 cases（92.5%）,the recurrence was 1 cases（2.5%）. The menstrual improvement rate and the recurrence rate of observation were statistically significant difference compared with the control group（P〈0.05）. Conclusion：The treatment of TCRP combined Norethisterone on endometrial polyps can significantly improve the menstrual disorders induced by endometrial polyp,and effectively reduce the recurrence of endometrial polyps,which is an ideal treatment method for endometrial polyps.