红细胞沉降率联合白细胞计数对男性代谢综合征患病风险分析

Analysis of the risk of associations of erythrocyte sedimentation rate and white blood cell with metabolic syndrome among male physical examination population in Taizhou city

目的探索台州市男性人群红细胞沉降率（ESR）和白细胞（WBC）计数与代谢综合征（MS）的关系,为MS的监测及预防提供理论依据。方法收集2012年14 505例浙江省台州医院男性体检者的临床症状和实验室指标资料,参照2004年中华医学会（CDS）推荐诊断标准对该人群进行MS诊断。结果该男性人群MS患病率为17.1%。MS患者ESR和WBC均显著高于非MS者（P〈0.001）。经年龄校准后,ESR〉11 mm/h组患MS的风险显著高于ESR≤11 mm/h组,OR为1.34（95%CI：1.22-1.48）;WBC〉7.7×10^9/L组患MS的风险显著高于WBC≤7.7×10^9/L组,OR为1.81（95%CI：1.64-1.99）;ESR〉11 mm/h且WBC〉7.7×10^9/L组相对于ESR≤11 mm/h且WBC≤7.7×10^9/L组人群患MS的危险度（OR：2.32,95%CI：2.00-2.70）显著高于ESR〉11 mm/h或WBC〉7.7×10^9/L组相对于ESR≤11 mm/h且WBC≤7.7×10^9/L组人群（OR：1.46,95%CI：1.33-1.60）。结论 ESR、WBC与MS有密切的联系,联合ESR和WBC对男性MS的监测及预防可起到重要的作用。

Objective The purpose of this study was to investigate the associations of erythrocyte sedimentation rate and white blood cell with metabolic syndrome among male physical examination population in Taizhou city,and provide the basis for the MS motoring and prevention. Methods Large amounts of clinical and laboratory data obtained from 14 505 Chinese male adults in an annual health screening in 2 012 was analyzed. The Chinese Diabetes Society 2004（ CDS 2004） criteria were used to define MS in this study. Results The prevalence of MS in wen was 17. 1%. After adjustment for age,the ESR 11 mm / h group at a significantly elevated risk for MS（ OR： 1. 34,95% CI： 1. 22- 1. 48） compared with the ESR ≤11 mm / h group,the 7. 7 ×10^9/ L group at a significantly elevated risk for MS（ OR： 1. 81,95% CI： 1. 64- 1. 99） compared with the WBC≤7. 7 ×10^9/ L group; the risk for MS in the ESR 11 mm / h and WBC 7. 7 ×10^9/ L group compared with ESR ≤11 mm / h and WBC≤7. 7 ×10^9/ L group（ OR： 2. 32,95% CI： 2. 00- 2. 70） significantly higher than the the ESR 11 mm / h or WBC 7. 7 ×10^9/ group compared with the ESR ≤11 mm / h and WBC ≤7. 7 ×10^9/ L group（ OR： 1. 46,95% CI： 1. 33- 1. 60）.Conclusion ESR and WBC has close relation with MS,and ESR comined with WBC has an important role in monitoring and preventing the MS in men.