原发性骨质疏松症的骨密度与中医脏腑辨证的相关性研究

Correlation Between BMD of Patients with Primary Osteoporosis and Viscera Differentiation

目的：探讨原发性骨质疏松症的骨密度与中医脏腑定位辨证之间的相关性。方法：对2010-2013年268例原发性骨质疏松人群进行中医脏腑辨证定位研究，另采用双能X线吸收法骨密度仪进行骨密度测定，测定部位包括L2-4椎体、左侧股骨颈和Ward＇s区。结果：原发性骨质疏松症中医辨证定位特点有一定规律，脏腑定位证候主要集中在肾，涉及肝、脾；各个证型骨密度平均值依次为：肾＜脾＜肝＜肺＜心，原发性骨质疏松症患者在同一部位不同脏腑间骨密度、骨矿盐水平比较，定位于肾与定位其他脏腑比较差异有统计学意义（P＜0.05）。结论：原发性骨质疏松症骨密度与脏腑定位中肾存在一定相关性，骨密度水平可作为原发性骨质疏松脏腑定位于肾的临床客观诊断指标。

Objective：To study the correlation between the bone mass density （BMD） of patients with primary osteoporosis and TCM syndrome differentiation of viscera positioning. Methods：Totally 268 cases of primary osteo-porosis patients from 2010 to 2013 were studied from the perspective of TCM syndrome differentiation of viscera positioning and determined the bone density by the dual-energy X-ray absorptionetry （DEXA）, the monitoring places including L2-4 vertebra, left femoral neck and Ward＇s zone. Results：There were certain laws in the characteristics of viscera syndrome differentiation, which showed that the viscera syndromes were mainly positioned in the kidney and involved liver and spleen;the average BMD levels in turn was kidney〈spleen〈liver〈lung〈heart, and the BMD and bone mineral density in the same place of different viscera were significantly different from that in the kidney and the differences had statistical meaning （P〈0.05）. Conclusion：The BMD of patients with primary osteoporosis have been correlated with kidney positioned by syndrome differentiation of viscera and the BMD levels can be the objec-tive diagnostic indexes for positioning kidney in clinic.