黄芪建中汤加味治疗消化性溃疡40例

The Modified HuangQi JianZhong Tang in Treating 40 Cases of Peptic Ulcer

目的:观察黄芪建中汤加味治疗消化性溃疡(PU)的临床疗效。方法:将80例PU患者随机分为对照组、治疗组各40例。对照组给予雷贝拉唑钠肠溶胶囊治疗,治疗组用黄芪建中汤加味治疗,2组均连续治疗4周。观察2组临床疗效、胃镜疗效及治疗前后症状积分的变化情况。结果:临床疗效、胃镜疗效总有效率治疗组分别为89.74%、86.2%,对照组分别为75.68%、71.4%,2组比较差异均有统计学意义(P<0.05)。症状积分2组治疗后均明显降低(P<0.05),治疗组降低更明显(P<0.05)。复发率治疗组为22.2%,对照组为58.3%,治疗组低于对照组(P<0.05)。结论:黄芪建中汤加味治疗PU疗效优于西医治疗,其疗效肯定,复发率低。

Objective： To observe the clinical effect of the modified HuangQi JianZhong Tang on patients with PU （peptic ulcer）. Methods： The 80 PU patients were randomized into the control and treatment group with 40 cases in each. The patients of the control group were administered rabeprazole sodium enteric-coated capsules and the cases in the treatment group given the modified HuangQi JianZhong Tang continuously for 4 weeks. The conditions of clinical effect, endoscopic findings and symptom indexes before and aider treatment were observed and compared between the two groups. Results： The total effective rates of the clinical and endoscopic effects in the treatment group were 89.74% and 86.2% respectively, while those in the control group were 75.68% and 71.4%, and those differences compared between the two groups had the statistical meaning （P〈0.05）; the symptom indexes of both groups markedly decreased （P〈0.05） and in the control group those indexes decreased more markedly （P〈0.05）; the recurrence rate of the treatment group was 22.2% and that of the control group was 58.3% higher than that in the treatment group （P〈0.05）. Conclusion： The modified HuangOi JianZhong Tang for the treatment of PU with low recurrence rate is superior to the western medicine and its clinical effect can be certain.