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非小细胞肺癌组织中人类白细胞抗原G的表达变化及意义 被引量：2

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摘要 目的观察非小细胞肺癌组织中人类白细胞抗原G(HLA-G)的表达变化,并探讨其临床意义。方法行肺癌切除术的非小细胞肺癌患者80例,术中取肺癌组织及癌旁正常肺组织,采用免疫组化SP法检测HLA-G,分析HLA-G表达与肺癌临床病理参数的关系。结果肺癌组织中HLA-G阳性表达率高于正常肺组织(P<0.05)。肺腺癌组织中HLA-G表达高于鳞癌,N1/N2、Ⅲa/Ⅲb期肺癌组织中HLA-G表达分别高于N0、Ⅰ/Ⅱ期(P均<0.05),不同性别、肿瘤大小的患者肺癌组织中HLA-G表达差异无统计学意义。结论非小细胞肺癌组织中HLAG呈高表达,可能参与了肺癌的发生发展。
作者 尚书恒
机构地区 泰安市肿瘤医院
出处 《山东医药》 CAS 北大核心 2015年第2期87-88,共2页 Shandong Medical Journal
关键词 非小细胞肺癌 人类白细胞抗原G 肿瘤标志物
分类号 R734.2 [医药卫生—肿瘤]
  • 相关文献

参考文献1

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共引文献16

同被引文献19

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山东医药
2015年 第2期

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