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肠出血性大肠杆菌O104单克隆特异性抗体的制备

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摘要 目的建立能够分泌针对肠出血性大肠杆菌O104表面抗原的特异性单克隆抗体,以期用于该病原菌的检测。方法用常规的骨髓杂交瘤融合技术。结果筛选到了2株针对肠出血性大肠杆菌O104血清型的特异性杂交瘤细胞株,凝集试验结果显示其具有良好的特异性。结论本研究筛选的单克隆抗体特异性强,敏感性高,可用于O104的检测或分离鉴定。
出处 《中国校医》 2015年第3期209-210,共2页 Chinese Journal of School Doctor
基金 国家科技重大专项(2012ZX10004-201 2013ZX10004-203-002) 国家自然科学基金(31100101)
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