摘要
临床统计证实了牙周炎与类风湿关节炎(RA)之间存在统计学意义上的相关性。牙周炎是最常见的口腔疾病之一,其特征是牙周附着和牙槽骨受到炎症破坏,而风湿性或其他炎症系统性疾病将促使牙周炎产生及其发展。近期的研究表明,RA较特异的因子——抗瓜氨酸蛋白抗体在牙周炎发病之前即可检测出来,能在一定程度上说明两种疾病的病理相关性,这一研究结论将为这两种疾病的预防和治疗提供更多的理论依据。
Clinical statistics has confirmed that there is statistical correlation between periodontitis and rheumatoid arthritis.Periodontitis is the most common oral disease,characterized by the inflammatory destruction of periodontal attachment and alveolar bone.The existence of a rheumatic or other inflammatory systemic disease may promote both the incidence and development of periodontitis.Recent studies have shown that anti-citrullinated protein antibodies（ACPA）,which are highly specific to rheumatoid arthritis,can be detected before the incidence of periodontitis,such result can partly explain the pathologic correlation between these two diseases,and will provide theoretical basis for the prevention and treatment of the two diseases.
出处
《医学综述》
2015年第7期1172-1174,共3页
Medical Recapitulate
关键词
牙周炎
风湿病
类风湿关节炎
抗瓜氨酸蛋白抗体
Periodontitis
Rheumatoid arthritis
Anti-citrullinated protein antibodies
