cIMT、Hcy检测在高血压病情评估及并发症预测中的应用价值

The Application of c IMT and Hcy in the Evaluation of Hypertension and the Prediction of Complications

高血压是以动脉血压持续升高为主要表现的慢性疾病,是动脉粥样硬化、冠状动脉粥样硬化性心脏病(冠心病)、脑卒中等多种心、脑血管疾病的重要危险因素。近年我国高血压患病率呈上升趋势,全国高血压患者已超3亿。颈动脉内膜中层厚度(c IMT)是检测动脉粥样硬化的无创性指标且与高血压危险分层密切相关,同型半胱氨酸(Hcy)通过损伤血管内皮细胞、诱导血栓形成、促进平滑肌增生等途径导致高血压病情进展并引起相应靶器官损伤。大量研究表明临床检测c IMT、Hcy对高血压病情评估及并发症预测十分重要。

Hypertension is an artery blood pressure rising as the main performance of chronic disease,it is an important risk factor of atherosclerosis,coronary heart disease,stroke and other kinds of heart,brain and vascular diseases.Recently the incidence of hypertension is rising in our country.The number of hypertensive patients is more than 300 million.Carotid intima media thickness（c IMT） is a noninvasive indicator for testing the atherosclerosis.It is also closely related with hypertension risk classification.High serum homocysteine（Hcy） is an independent risk factor for hypertension.It leads to high blood pressure and corresponds target organ complications by injuring the vascular endothelial cells,promoting intravascular thrombosis,and causing vascular smooth muscle hyperplasia.There are many researches show that it is very important to test c IMT and Hcy on hypertensive patients for disease assessment and the prediction of complications.