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基因重组活化凝血因子FⅦ在心血管手术中的应用 被引量:2

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摘要 心血管手术围术期的高出血和输血风险及其带来的并发症一直是影响患者转归的重要因素。由于疾病本身、外科操作和体外循环过程(cardiopulmo-nary bypass,CPB),凝血因子在血液中的浓度呈下降趋势,严重者会导致凝血异常,增加出血和异体输血风险。及时纠正凝血功能缺陷,对于减少患者术中及术后出血有重要意义。
出处 《北京医学》 CAS 2015年第4期383-385,共3页 Beijing Medical Journal
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  • 1Karkouti K, Wijeysundera DN, Yau TM, et al. The independent as- sociation of massive blood loss with mortality in cardiac surgery[J]. Transfusion, 2004, 44:1453-1462.
  • 2Lee AI, Campigotto F, Rawn JD, et al. Clinical significance of coag- ulation studies in predicting response to activated recombinant Fac- tor VI in cardiac surgery patients[J]. Br J Haemotol, 2012, 157:397- 400.
  • 3Elizalde M, Slobodskoy L, Diodato M, et al. Use of Recombinant Factor VII in cardiac surgery[J]. Recent Pat Cardiovasc Drug Dis- cov, 2012, 7:216-220.
  • 4Hedner U, lnqerslev J. Clinical use of recombinant F VI a(rF VII a)[J]. Transfus Sci, 1998, 19:163-176.
  • 5Lodge JP, Jonas S, Jones RM, et al. Efficacy and safety of repeated perioperative doses of recombinant factor Vla in liver transplantation [J]. Liver Transpl, 2005, 11:973-979.
  • 6Kenet G, Walden R, Eldad A, et al. Treatment of traumatic bleeding with recombinant factor Vlla[J]. Lancet, 1999, 354:1879.
  • 7Phillip LE, McLintock C, Pollock W, et al. Recombinant activated factor W in obstetric hemorrhage: experiences from the Australian and New Zealand Haemostasis Registry[J]. Anesth Analg, 2009, 109: 1908-1915.
  • 8O' Connell KA, Wood J J, Wise RP, et ah Thromboembolie adverse events after use of recombinant human coagulation factor Wl a[J]. JAMA, 2006, 295:293-298.
  • 9A1-Ruzzeh S, Navia JL. The "off-label" role of recombinant factor V in surgery: is the problem deficient evidence or defective con- cept?[J]. J Am Coil Surg, 2009, 209:659-667.
  • 10Uber WE, Toole JM, Strand MR, et al. Administration of recombi- nant activated factor VII in the intensive care unit after complex car- diovascular surgery: clinical and economic outcomes[J]. J Thorac Cardiovasc Surg, 2011,141:1469-1477.

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