摘要
微流控芯片电泳技术作为一种消耗少、速度快、效率高的分析技术,可同时实现便携化、集成化、高通量,在临床检测中发挥着重要作用。该文综述了近年来微流控芯片电泳技术在临床应用方面的研究进展,主要包括微流控芯片电泳技术在小分子、氨基酸、蛋白质、核酸、细胞等方面的应用近况。同时,介绍了一种崭露头角的基于大管电泳技术的大通道电泳微流控芯片技术,最后对微流控芯片电泳技术实现临床分析进行了展望。
As a low consumed,rapid,efficient technology,microchip electrophoresis which is also portable,integrated,and high-throughput,plays an important role in application of clinical analysis. In this paper,the advantages of microchip electrophoresis are introduced concisely. The latest advances of microchip electrophoresis in clinical applications are reviewed,including the developments in small molecules,amino acids,proteins,nucleic acids,as well as cells. And a newly developed method will be used in two- dimensional analysis, and a new wide channel microchip（WCC） system is established. The developments for the future are also discussed.
出处
《分析测试学报》
CAS
CSCD
北大核心
2015年第4期477-482,共6页
Journal of Instrumental Analysis
基金
国家自然科学基金面上项目(21375093)
高等学校博士学科点专项科研基金资助项目(20130032120081)
天津大学自主创新基金资助项目(1102213)
关键词
微流控芯片
毛细管电泳
大管电泳
临床检测
综述
microchip
capillary electrophoresis
wide bore electrophoresis
clinical analysis
review
