摘要
调查1997年4月至1997年9月出院病例服用氯丙嗪的精神病患者389例,出现药物副反应的为200例(51.4％),其中心电图改变者131例(65.5％),锥体外系副反应57例(28.6％),SGPT升高52例(26.0％),脑电图改变26例(13.0％),皮疹22例(11.0％),胃肠道副反应16例(8.0％),造血系统副反应12例(6.0％),体位性低血压9例(4.5％),内分泌系统副反应4例(2.0％),其他12例(6.0％)。对上述副反应发生的原因和处理作了分析。
Three hundred and eighty - nine hlopromazine-treated psychotic patients discharged from April to Saptember, 1997 were investigated. The incidence of drug side effects was 51. 4%(200 cases). Among them,131 developed EKG changes (65. 5%), 57 extrapyramidal side effect (28. 6%), 52 SGPT elevation (26. 0%),26 EEG Changes (13. 0%),22 dermatitis(11. 0%),16 gas-trointestinal side effects (8. 0%) ,12 haematological side effecsts (6. 0%) ,9 postural hypotension (4. 5%),4 endorine symptoms(2. 0%),12 the other symptoms(6. 0%). The causes and treatment of these side effects were analyzed.
