选择性IgA缺乏的检测及输血

The detection and transfusion of selective IgA deficiency

随着输血医学的发展，临床溶血性输血反应已经比较少见，而由于输注血浆成分导致的输血过敏反应越来越引起重视，其中有一部分较少见的严重的输血过敏反应是由抗-IgA导致的，IgA缺乏症者体内会产生抗-IgA，当输注含IgA的血液成分时可导致严重的过敏反应发生，甚至危及患者生命。因此，对选择性IgA缺乏症（selective IgA deficiency，SIgAD）患者的检测及输血应引起高度重视。

Now transfusion medicine pay more and more attention to anaphylactic transfusion reactions in IgA-deficient individuals,we make a summary about the laboratory examination methods and transfusion strategies of IgA-deficient to provide a reference for IgA deficiency patients blood transfusion,prevent the happening of anaphylactic transfusion reactions.