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CK-MM亚型用于肌营养不良症疗效判定的初步研究 被引量:2

Primary study of CK-MM used to determine the curative effect of muscular dystrophy
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摘要 目的 研究CK MM亚型用于肌营养不良症疗效判定的价值。方法 使用Sebia公司生产的全自动蛋白电泳仪分离CK MM亚型 ,扫描仪扫描测定。结果 疗效较好的 3例患者均表现为MM3、MM2 降低而MM1 相对增高 ,MM2 MM1 比值降低。结论 CK Objective To investigate the significance of CK MM isoforms to determine the curative effect of muscular dystrophy.Methods CK MM isoforms were separated by fully automatic protein electrophresis apparatus produced by Sebia company and scaned by scaning appartus.Results Three patients with muscular dystrophy of better curative effect were selected.Their MM 3 and MM 2 in blood serum all decreased and MM 1 increased relatively.Conclusion CK MM isoforms can be an important index to determine the curative effect of muscular dystrophy.
出处 《河北医药》 CAS 2002年第8期624-625,共2页 Hebei Medical Journal
关键词 治疗 遗传性变性疾病 肌萎缩 CK-MM亚型 肌营养不良症 疗效判定 muscular dystrophy CK MM isofroms curative effect electrophoresis
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  • 1Audrey SP,et al.Muscular dystrophy in young girl.Neurology,1970,20:147.
  • 2Hood D,et al.Serum enzyme alterations in chronic muscle disease.Clinical Chemistry,1991,95:402.
  • 3Yasmineh WG,et al.Postsynthetic variants of creatine Kinase MM.J Lab.Clin Med,1981,98:109.
  • 4Page S,et al.Isoforms of creatine kinase:MM in the study of skeletal muscle damage.Eur J Clin Ives,1989,19:185.
  • 5Leal AM,et al.Relations between delayed diagnosis and forms of onset in Duchenne muscular dystrophy. Gac Med Mes,1994,130:459.

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