卡前列素氨丁三醇治疗产后出血的可行性研究

目的研究卡前列素氨丁三醇在治疗产后出血中的临床疗效。方法选取产后出血患者80例,随机均分为2组(n=40)。胎儿娩出后,实验组给予卡前列素氨丁三醇及缩宫素,对照组给予米索前列醇及缩宫素,观察2组患者产后2 h出血量、止血时间及不良反应发生情况。结果在产后2 h出血量、止血时间,总有效率方面比较,差异有统计学意义(P<0.05)。实验组出现2例胃肠道反应,对照组出现3例胃肠道反应,停药后不良反应消失。结论卡前列素氨丁三醇治疗产后出血安全可靠,疗效确切,值得临床推广应用。

Objective To study the clinical effects of carboprost tromethamine in the treatment of postpartum hemorrhage.Methods 80 patients with postpartum hemorrhage were randomLy divided into experimental group and control group, each group was 40.After delivered, experimental group was given carboprost tromethamine and oxytocin, while control group was given misoprostol and oxytocin.The two groups were observed in 2 hours bleeding amount, bleeding time and adverse reaction.Results There was significant difference between the two groups in 2 hours bleeding amount, bleeding time, adverse reaction and total effective rate（P〈0.05）. 2 cases of gastrointestinal reaction was occurred in experimental group while 3 in the control group.Adverse reaction disappeared since the medication was stopped.Conclusion The use of carboprost tromethamine in postpartum hemorrhage is safe and effective, worthy of clinical application.