盐酸氨溴索不同给药方式治疗小儿支气管肺炎的疗效观察

Observation of ambroxol by different administration methods in treating the children with bronchial pneumonia

目的探讨盐酸氨溴索不同给药方式治疗小儿支气管肺炎的临床疗效。方法将234例小儿支气管肺炎患者随机分为甲、乙、丙三组,在常规治疗的基础上均给予盐酸氨溴索治疗,分别采用雾化吸入、静脉滴注、口服三种方式,治疗后观察三组患者的临床疗效以及症状改善情况。结果在临床疗效方面,甲组临床总有效率最高,但与乙组和丙组的差异不具有显著性;在症状改善情况来看,甲组症状改善时间明显低于乙组和丙组,差异具有统计学意义(P<0.05)。结论雾化吸入盐酸氨溴索治疗小儿支气管肺炎的临床疗效最佳,可加快改善临床症状,值得在临床上大力推广。

Objective To discuss the clinical effects of ambroxol hydrochloride by different administration methods in treating children with bronchial pneumonia. Methods 234 cases of children with bronchial pneumonia were divided into A、B、C three groups. On the basis of routine treatment were treated with ambroxol hydrochloride.Respectively used by aerosol inhalation, intravenous and oral after Conventional treatment. Then observed the clinical effects. Results The clinical effects of group A were higher than group B and C. There was no statistically significant difference（P〉0.05）. Symptoms improve effectively within a shorter time in group A than group B and C with a significant difference（P〈0.05）. Conclusion Ambroxolhydrochloride by aerosol inhalation in children with bronchial pneumonia can improve the clinical effect, shorter the symptoms improve time and was worth promoting in clinic practice.