联合应用蒲参胶囊和泼尼松治疗原发性肾病综合征的临床观察

Treatment of Pushen Capsule and Prednisone in primary nephrotic syndrome patients

目的观察联合蒲参胶囊和泼尼松治疗原发性肾病综合征的临床疗效。方法 72例肾病综合征患者随机分成两组,泼尼松组(对照组)、蒲参胶囊组(泼尼松+蒲参胶囊),观察两组患者治疗前后尿蛋白、血浆白蛋白、血脂变化。结果两组治疗后均见尿蛋白减少,血浆白蛋白升高和总胆固醇、甘油三酯下降(P<0.01),但蒲参胶囊组和对照组相比,蒲参胶囊组作用尤为明显(P<0.01)。结论蒲参胶囊能减少尿蛋白量,提高血浆白蛋白,降低血脂。

Objective： To observe therapeutic effect of Pushen Capsule and Prednisone in treatment of primary nephrotic sysdrome. Methods： Seventy-two patients were divided into two groups at random： Group A was treated with Prednisone,and Group B treated with Prednisone and Pushen Capsule. The changes in their urine,protein,serum albumin and blood fat after the treatment were observed. Results： The decrease of urine protein,increase of serum albumin and lowering in total cholesterol and triglyceride were found in the two groups（ P〈 0. 01）. The group treated with Pushen Capsule are more significant than the other group（ P〈 0. 01）. Conclusion： Pushen Capsule can decrease urine protein,increase serum albumin and lower blood fat level.