慢性心力衰竭患者尿酸变化的临床价值探讨

Clinical Value of Uric Acid Change in Patients with Chronic Heart Failure

目的:探讨尿酸(UA)变化规律及对预后的影响。方法:观察140例慢性心力衰竭患者UA水平及高尿酸血症(HUA)发生率;探讨慢性心力衰竭患者不同心功能分级UA水平与LVEDd、LVEF相关性,对慢性心力衰竭患者进行随访。结果:慢性心力衰竭患者UA水平(498.63±138.56)μmol/L,HUA患者42.86%;随着心功能分级增加UA水平升高,HUA发生率相应增加(P<0.05);UA升高LVEDd增加、LVEF降低(P<0.05),随访(2.69±0.65)年,HUA组死亡、每年住院次数、住院时间时间高于HUA正常组(P<0.05)。结论:慢性心力衰竭HUA发生率较高,对预后有不良影响,UA可用于慢性心力衰竭的严重程度及预后评估。

Objective：To study the change of UA and the influence on prognosis.Methods：The effects of UA level in patients with chronic heart failure and 140 cases of hyperuricemia（HUA） in patients with chronic heart failure incidence;not concentric UA level and LVEDd,LVEF classification function correlation,follow-up on patients with chronic heart failure.Results：The level of UA in patients with chronic heart failure（498.63±138.56）μmol/L,42.86% HUA patients with heart function classification;increase the level of UA increased,the incidence of HUA increased（P〈0.05）;UA elevated LVEDd increased,LVEF decreased（P〈0.05）,（2.69±0.65） years of follow-up,the HUA group of death,hospitalization the number of hospitalization time,higher than the normal HUA group（P〈0.05）.Conclusion：Chronic heart failure incidence of HUA is high,have adverse effects on prognosis,UA can be used for evaluating the severity and prognosis of chronic heart failure.