ERCP胆管支架在恶性胆管梗阻中的临床应用#

Clinical Application of ERCP Biliary Stents in Malignant Biliary Obstruction

目的:为了进一步研究和探讨在采用胆管支架引流术治疗恶性胆管梗阻的实践过程中,分别采用金属支架和塑料支架实施治疗后的临床治疗效果差异,从而为临床实践研究提供可靠依据。方法:本文选取了我院2006年6月至2013年12月期间收治恶性胆管梗阻患者88例为研究对象,根据患者所采用支架的不同进行分组,分成金属支架组(16例)和塑料支架组(72例),观察两组患者采用不同临床治疗方法后的TBIL、ALT、ALP、GGT、TNF-α和30d后死亡发生率及支架阻塞发生率。结果:(1)在ALP、GGT、TNF-α等三项指标上,组间比较,金属支架组患者的指标水平均显著的优于塑料支架组;(2)在平均生存时间、支架开通时间两项指标上,组间比较,金属支架组患者均长于塑料支架组。结论:与采用塑料支架相比较,采用金属支架实施ERCP胆管支架术治疗的效果更好,是临床针对恶性胆管梗阻实施胆管支架引流治疗的可靠选择。

To further study and discuss the differences of the clinical treatment of the application of metal stents and plastic stents in the course of malignant biliary stent drainage of bile duct obstruction, so as to provide reliable basis for clinical practice research.Methods：88 patients of malignant biliary obstruction from June 2006 to December 2013 in our hospital were chosen as the research object. According to the differences of stents, they were divided into the metal stent group （16 cases） and the plastic stent group （72 cases）. The TBIL, ALT, ALP, GGT, TNF-α, and the incidence of mortality and incidence of stent occlusion after 30 days for the two groups after different clinical treatment methods were observed.Results： （1） In the three indicators of ALP, GGT, TNF-α, etc compared between the two groups, the indicator of the metal stents was signiifcantly better than the plastic stent group.（2） In the average survival time and stent patency time two indicators, compared between the two groups, the metal stents was signiifcantly longer than the plastic stent group. Conclusion： Compared with plastic stents, the treatment effect of the metal stents and with the implementation of ERCP biliary stenting is better, and it is the reliable choice for malignant biliary obstruction implementation of clinical biliary stent drainage treatment.