三种抗生素治疗胸外科术后感染的最小成本分析

Cost Minimization Analysis on Three Kinds of Antibiotics in Treating Thoracicsurgery Postoperative Infection

目的:评价3种抗生素(头孢呋辛、头孢美唑和拉氧头孢)治疗胸外科术后感染的成本-效果。方法:采用回顾性分析,对103例分别采用头孢呋辛、头孢美唑和拉氧头孢治疗胸外科术后感染的效果进行最小成本分析。结果:头孢呋辛组、头孢美唑组和拉氧头孢组的成本分别为(1022.4±293.4)元、(1584.2±625.3)元和(4780.3±1504.8)元(P<0.05),有显著性差异;有效率分别为88.6%、79.4%和88.2%(P>0.05),无显著性差异。结论:头孢呋辛治疗胸外科术后感染有明显的药物经济学优势。

Objective： To evaluate the cost and the effect of treatment of thoracicsurgery postoperative infection using three kinds of antibiotics（cefuroxime, cefmetazole, and latamoxef）. Methods： Retrospective analyze 103 cases, analyze the minimization cost of the effect of treatment of thoracicsurgery postoperative infection using cefuroxime, cefmetazole, and latamoxef. Results： The cost of cefuroxime group, cefmetazole group, and latamoxef group are（1022.4±293）.4 yuan,（1584.2±625.3） yuan, and（4780.3±1504.8） yuan（P〉0.05） respectively, with significant difference; the effective rates are 88.6%, 79.4%, and 88.2%（P〈0.05） respectively, with no significant difference. Conclusion： Cefuroxime has significant pharmacoeconomic advantage in treatment of thoracicsurgery postoperative infection.