北方农村地区男性代谢综合征与饮酒关系研究

Association study between metabolic syndrome and alcohol consumption among rural male residents in northern China

目的了解北方农村地区男性代谢综合征（metabolic syndrome,MS）现状及其与饮酒的关系。方法采用整群随机抽样的方法,在甘肃榆中县、北京顺义区、吉林东丰县和吉林靖宇县等4个区县分别抽取4个村。每个区县分别调查〉35岁人群1 250人,男女各半。各村平均分配样本量。收集吸烟、饮酒、血压、身高、体重等相关因素资料并采集血样。将人群分为不饮酒、少量饮酒（〈20 g/d）、中量饮酒（20-80 g/d）和大量饮酒（〉80 g/d）四组。选取其中的2 062例男性进行分析。MS定义选用中国糖尿病学会的标准。用多因素非条件Logistic回归方法分析饮酒与MS的关系。结果调查对象平均年龄（55.9±10.8）岁,41.4%饮酒。MS患病率为11.6%,饮酒者（13.1%）高于不饮酒者（10.5%）（χ^2=3.30,P=0.069）。MS患病率随着饮酒量（Z=39.08,P〈0.001）和饮酒频率（Z=39.65,P〈0.001）的增加上升。调整其他因素后,中量以上饮酒可显著增加MS患病风险（均有P〈0.05）;饮酒频度与MS关系并不显著（均有P〉0.05）。结论在男性人群中,中量饮酒可增加MS风险。应该给与针对性的干预,限制饮酒量。

Objective To explore the present condition of metabolic syndrome（ MS） and the relationship between MS and alcohol consumption among rural residents in Northern China. Methods A cross-sectional study was conducted using stratified cluster random sampling in northern China（ Shunyi,Beijing; Yuzhong,Gansu; Dongfeng and Jingyu,Jilin） in 2013. Four villages were randomly selected from each designated county. About 1 250 participants,aged over 35 years,half men and half women,were recruited from the villages. Information of smoking,drinking,blood pressure（ BP）,height,weight,and blood samples were collected. Participants were categorized into four alcohol consumption classes（ no drinking,light consumption（〈 20 g / d）,moderate consumption（ 20-80 g / d）,heavy consumption（ 〉80 g / d））.Men（ 2 062 persons） were analyzed. The Chinese Diabetes Society＇s definition of MS was adopted. Logistic regression was used to find the association between alcohol consumption and MS. Results The average age of participants was（ 55. 9 ±10. 8） years old,current drinkers were 41. 4%. The prevalence of MS was 11. 6%,higher among current drinkers than no drinkers（ 13. 1% vs. 10. 5%,χ^2= 3. 30,P = 0. 069）. The prevalence of MS were rising with the increasing of quantity（ Z = 39. 08,P〈 0. 001） and frequency（ Z = 39. 65,P 〈0. 001） of alcohol consumption. After adjustment,the risk of MS was increased with moderate alcohol consumption or more（ P〈0. 05）,but not with the frequency of alcohol consumption（ P〈0. 05）. Conclusions The risk of MS was increased with moderate alcohol consumption or more among men. Advice of limited alcohol consumption is helpful to reduction of the prevalence of MS.