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一种含氟pH值响应性聚合物的制备

A Kind of Fluorine Containing pH Responsive Polymer Preparation
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摘要 通过无皂乳液聚合制备了一种具有p H值响应型的聚合物Poly(TFEMA-DMAEMA-PEGMA),通过红外、核磁、测定了聚合物的结构。通过激光粒度仪和Zeta电位仪测定了聚合物胶束在不同的pH值的磷酸盐缓冲溶液中响应行为,该聚合物可能用于在不同p H值中药物释放载体。 A kind of pH - responsive （ DMAEMA - TFEMA - PEGMA） were prepared via surfactam - free emulsion polymerization. The chemical structure of the copolymers was characterized by Fr- IR, NMR. The particles were studied by dynamic light scattering, and zeta potential measurement ; the polymer displayed a significant pH - responsive behavior. This study suggests that the poly （DMAEMA- TFEMA- PEGMA） have potential applications as a-ntrolled drug release carrier.
作者 孙崇彬 张书香 李义滨
机构地区 济南大学化学化工学院
出处 《山东化工》 CAS 2015年第8期6-8,共3页 Shandong Chemical Industry
基金 国家国际科技合作专项子项目(2012DFA70870-3)
关键词 pH值响应性 甲基丙烯酸二甲基氨乙酯 甲基丙烯酸三氟乙酯 pH- responsive I DMAEMA ITFEMA
分类号 O632.3 [理学—高分子化学]
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参考文献7

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共引文献1

山东化工
2015年 第8期

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