中医辨证施治慢传输性便秘40例临床观察

Clinical Observation on 40 cases of TCM Syndrome Differentiation and Treatment of Slow Transit Constipation

目的:观察中医辨证治疗慢传输型便秘(STC)的临床疗效。方法:80例STC患者随机分为治疗组(A组)和对照组(B组)各40例。A组给予中医辨证施治,每日1剂,共30天。B组予莫沙必利片口服,每次5mg,每日3次,共30天。分别观察患者治疗前后大便性状评分、每周自主排便次数和结肠传输试验结果,比较两组患者治疗有效率。结果:总有效率:A组为90%;B组为82.5%,两组相比无统计学差异。治疗后两组患者每周完全自发性排便次数均较治疗前显著增加(P<0.05),大便性状评分:A组比治疗前明显好转(P<0.05),B组比治疗前无明显差异(P>0.05)。治疗后两组大便性状评分和排便次数比较无统计学意义。结肠传输试验结果显示,治疗后两组残留标记物数目都明显低于治疗前(P<0.05),但组间比较无统计学意义(P>0.05)。结论:中医辨证施治STC,可缓解便秘的症状,使大便性状恢复接近正常,长期服用效果好。

Objective：To observe the clinical curative effect of TCM treatment in slow transit constipation（STC）. Methods：80 cases of STC were randomly divided into the treatment group （A group） and control group （group B） with 40 cases in each. Group A was treated with TCM syndrome differentiation, daily 1 agent, a total of 30 days. Group B was treated with Mosapride tablets orally, 5mg each time, 3 times a day, a total of 30 days. The stool score, the weekly independent defecation frequency and colonic transit test results of the patients were observed before and after treatment. The treatment efifciency of patients in two groups were compared. Results：The total effective rate：A group was 90%;B group was 82.5%.No signiifcant difference between the two groups. After the treatment of two patients weekly complete spontaneous defecation times than before treatment signiifcantly increased （P〈0.05）, stool score：A group than before treatment signiifcantly improved （P〈0.05）, B group than before treatment had no signiifcant difference （P〉0.05）. The two groups after treatment stool score and defecation frequency showed no statistical signiifcance. Colonic transit test results show, the two groups after treatment of residual marker number was obviously lower than that before treatment （P〈0.05）, but no statistical signiifcance between the two groups（P〉0.05）. Conclusions：The TCM syndrome differentiation and treatment of STC, can ease the symptoms of constipation, the stool was close to normal, with good effect if taken long-term.