呼吸内科病房铜绿假单孢菌感染的耐药性变迁分析

Resistance Diversity Analysis of Infection in Respiration Department Caused by Pseudomonas Aeruginosa

目的:分析呼吸内科病房铜绿假单胞菌感染的耐药性变迁。方法:收集2008年1月至2013年12月呼吸内科住院患者送检的痰标本,分离出铜绿假单胞菌236例,对常用的16种抗菌药物进行耐药性回顾分析。结果:236株来源于痰液的铜绿假单胞菌标本耐药率总体呈上升趋势,16种抗菌药物中4种抗菌药物耐药率下降,6种抗菌耐药率均有上升。结论:铜绿假单胞菌对使用量大的抗菌药物耐药率逐年升高,多重耐药菌出现较普遍,应根据药物敏感试验结果选择使用抗菌药物。

Objective：To analyze the change of resistance spectrum of Pseudomonas aeruginosa in infectious patients in Respiratory Medicine Ward, and to instruct the physician to administer drugs reasonably. Methods：Pseudomonas aeruginosa in infectious from Respiratory Medicine Ward were collected during the last sixyears. The constituentratio and the resistance status of the Pseudomonas aeruginosa in infectious were analyzed. The resistance spectrum of Pseudomonas aeruginosato16 common antibacterials were analyzed. Results：A total of 236 strains of Pseudomonas aeruginosa were isolated from sputum. The sensitive rates of Pseudomonas aeruginosa to 4 kinds of antibiotics were in a slightly downtrend. The sensitive rates of Pseudomonas aeruginosa to 9 kinds of antibiotics were in a slightly uptrend. Conclusions：Pseudomonas aeruginosa is resistant many commonly used antibiotics and multiple drug resistance is more common. It is important for us to control antibiotic resistance by using antibiotics reasonably.