胸段食管癌全程调强放疗与后程陀螺刀治疗的近期疗效观察

Recent Outcome of Thoracic Esophageal Carcinoma: The Whole Intensity-modulated Radiotherapy Versus Late Course Gyroscope

目的观察、比较胸段食管癌全程调强放疗与后程陀螺刀治疗的近期疗效及近期放疗副反应。方法将符合条件的食管癌患者60例随机分为A组亦即治疗组(全程调强放疗)和B组亦即对照组(前期调强放疗+后程陀螺刀治疗),分阶段治疗,前阶段治疗结束时、全部放疗结束后1个月评价病情,复查胸部CT及食管钡餐,评价疗效。结果 A组近期疗效86.7%(26/30),B组近期疗效83.3%(25/30)。A组Ⅲ-Ⅳ度急性放射性食管黏膜炎30%(9/30),B组Ⅲ-Ⅳ度急性放射性食管黏膜炎40%(12/30),两组均未出现急性Ⅲ-Ⅳ度放射性肺炎。结论食管癌全程调强放疗与后程陀螺刀治疗的近期疗效显著,后程陀螺刀治疗并发急性食管黏膜炎较重,但疗程缩短,亦不失为一种有效的治疗手段。

OBJECTVE To observation recent outcome and side effect on the radiotherapy of thoracic esophageal carcinoma using the whole intensity-modulated radiotherapy（IMRT） compared with late course gyroscope. METHODS to esophageal earcinoma patients who qualify were random divided into the whole IMRT group（30 patients, A group） and late course gyroscope group. Treatment was divided into the front stage and the later stage. Patients underwent chest CT and barium meal to evaluate curative effect at the time of the front stage finishing and one month after all the treatment finished. RESULTS Recent outcome of A and B is 86.7%（26/30） and 83.3%（25/30）. llI-IVaeute esophageal mueosal inflammation of group A was 30%（9/30） and group B was 40%（12/30）. Both of two groups were not m-IV acute radioactive pneumonia. CONCLUSION Recent outcome on the radiotherapy of thoracic esophageal carci- noma using the whole IMRT and late course gyroscope was remarkable. Although acute esophageal mueosal inflammation in the late course gyroscope treatment group was worse than the whole IMRT group, but the treatment time was shorter, so it was a effective treatment.