国内外破伤风相关疫苗的质量参数比较

Comparison of Quality Parameters of Domestic and Imported Tetanus-based Combined Vaccines

目的了解基础免疫阶段在我国市场上主要使用的国内外破伤风相关疫苗的关键质量参数及其水平。方法以国内外各厂家分别生产的10批次产品为依据,对其质量数据进行统计、分析和比较。结果国产产品和进口产品各有其优势所在,同时也均有需进一步提升的空间。结论期望更多国内外疫苗厂家能针对自身产品特点,进一步提高产品质量,在未来制造出更安全、有效且使用便捷的新型疫苗。

OBJECTIVE To investigate the situation of the key quality parameters of the main domestic and imported tetanus- based combined vaccines used in the basic immunization phase in our country. METHODS The quality parameters of 50 batches of vaccine products which were manufactured respectively by domestic and foreign manufacturers were analyzed and compared. RESULTS AND CONCLUSION Domestic and imported tetanus-based combined vaccine products have different advantages and the quality and these products may be improved further in some respects. It is suggested that more domestic and foreign vaccine manufacturers improve the product quality based on the characteristics of their own products to provide safer and more effective vaccines that can also more convenient for use in the future.