1例妊娠甲状腺功能亢进综合征引起肝损伤的药学监护

Pharmaceutical Care for a Case of Liver Injury Caused by Gestational Hyperthyroidism

目的探讨1例临床药师参与妊娠甲状腺功能亢进综合征引起肝功能损伤的药学监护。方法跟踪1例妊娠甲状腺功能亢进和肝功能损伤的患者妊娠期间主要诊疗经过,结合患者病史、妊娠期间的相关检查,分析其甲状腺功能亢进及肝损的原因,进而对临床用药提出合理化建议。结果患者患有妊娠甲状腺功能亢进综合征,进而引起肝功能损伤,在未经药物干预下,患者甲状腺功能随着妊娠周期延长明显好转。随着甲状腺功能亢进症状的好转,通过2种治疗肝损伤药物的联合应用,患者肝功能也逐步恢复正常。结论临床药师参与妊娠甲状腺功能亢进综合征引起肝功能损伤患者的药物治疗,可以促进临床合理用药,提高妊娠期患者用药的安全性。

OBJECTIVE To explore one case of clinical pharmacist participating in pharmaceutical care for patient with liver injury caused by gestational hyperthyroidism. METHODS Tracing the diagnosis and treatment process of one patient who had liver injury and gestational hyperthyroidism. According to the medical history and inspections during pregnancy to analyze the cause of liver injury and gestational hyperthyroidism, and then gave the rationalization suggestion for clinical medication. RESULTS Patient suffered from liver injury caused by gestational hyperthyroidism. As the pregnancy time went by, the patient＇s thyroid function was improved markedly without drug intervention. Through the combined use of two drugs in the treatment of liver injury, the liver function also gradually returned to normal with the improvement of hyperthyrodidism. CONCLUSION Clinical pharmacist participating in drug treatment for patient with liver injury caused by gestational hyperthyroidism can promote rational use of drugs in the clinic, improve the safety use of drugs in pregnant women.