基于LS-SVM测量生物组织光学参量的实验研究

Experimental study about measurement of optical parameters of biological tissue based on least square support vector machine

为了实现无损测量生物组织光学参量,利用CCD技术结合最小二乘支持向量机,对测量组织模拟液的光学参量进行了实验研究。通过实验测量了组织模拟液的表面漫反射光分布,建立了漫反射光分布与光学参量间的最小二乘支持向量机回归模型,该模型实现了小样本条件下对组织模拟液光学参量的预测误差仅为5%。结果表明,最小二乘支持向量机结合CCD测量技术能够准确测量组织模拟液的光学参量。

In order to achieve non-destructively measurement of optical parameters of biological tissue,optical parameters of tissue simulation phantoms were measured in experiments based on CCD technology and least square support vector machine（ LS-SVM）. From the experiment,the diffuse reflectance distribution of tissue simulation phantoms was measured. The LS-SVM regression model between the optical parameters and the corresponding diffuse reflectance distribution was founded. The prediction average error of the optical parameters of the tissue simulation phantoms was only5% under small sample conditions. The results show that combination of CCD measurement technology and LS-SVM can measure the optical parameters of tissue simulation phantom accurately.