摘要
目的:观察疏肝健脾针刺法治疗抑郁障碍的临床疗效。方法:将105例患者随机分为3组,疏肝健脾针刺组、非经非穴组和西药组,各35例。3组均治疗8周,观察3组临床疗效,并依据汉密尔顿抑郁量表(HAMD-17)评分及生活质量综合评定量表(GQOLI-74)对治疗效果及生活质量进行评定。结果:(1)入组8周时,疏肝健脾针刺组总有效率为90.00%、非经非穴组为64.29%、西药组为90.91%,疏肝健脾针刺组和西药组优于非经非穴组(P<0.05);治疗后3个月,疏肝健脾针刺组总有效率为93.33%、非经非穴组为71.43%、西药组为87.88%,疏肝健脾针刺组优于非经非穴组和西药组(P<0.05)。(2)入组8周时,疏肝健脾针刺组与西药组相比,HAMD-17减分率与GQOLI-74总分没有显著差异(P>0.05)。(3)治疗后1个月、治疗后3个月时,疏肝健脾针刺组与西药组相比,HAMD-17减分幅度与GQOLI-74总分相比有显著性差异(P<0.01)。结论:疏肝健脾针刺可以显著改善抑郁障碍患者的HAMD-17与GQOLI-74评分,近期疗效与西药相当,但远期疗效优于西药治疗。其疗效的持续可能与针刺对机体的整体调整有关。
Objective:To observe the acupuncture of strengthening spleen and soothing liver method on patients with major depressive disorder(MDD).Methods:Totally 105 cases of MDD were randomized into three groups:observation group(acupuncture of strengthening spleen and soothing liver method,n = 35),non-acupoints group(n = 35) and medicine group(n = 35).Three groups were treated for 8 weeks and then we observed the clinical curative effect.The therapeutic effect was evaluated with the Hamilton Rating Scale for Depession-17 items(HAMD-17) and the Generic Quality of Life Inventory-74(GQOLI-74).Results:(1) The total effective rates of the observation group,non-acupoints group and medicine group were 90.00%,64.29%and 90.91% after 8 weeks' treatment respectively and the total effective rates of the observation group and western medicine group were superior to that of the non-acupoints group(P〈0.05).The total effective rates of the observation group,non-acupoints group and medicine group were 93.33%,71.43% and 87.88% 3 months after treatment and the total effective rate of the observation group was superior to that of the non-acupoints group and medicine group(P〈0.05).(2) There were no significant differences between the observation group and western medicine group on the scores of HAMD-17 and GQOLI-74 after treatment(P〉0.05).(3) There were significant differences between the observation group and medicine group in the scores of HAMD-17 and GQOLI-74 1 and 3 months after treatment(P〈0.01).Conclusion:The acupuncture of strengthening spleen and soothing liver method can obviously improve the scores of HAMD-17 and GQOLI-74.Its recent curative effect is the same as that of the western medicine,but the long-term curative effect is superior to that of western medicine with more persistence.
出处
《辽宁中医杂志》
CAS
北大核心
2015年第4期842-845,共4页
Liaoning Journal of Traditional Chinese Medicine
基金
重庆市教委课题(KJ100321)
关键词
抑郁障碍
疏肝健脾
针刺
major depressive disorder
strengthening spleen and soothing liver
acupuncture