体外冲击波治疗慢性非结石性胆囊炎的临床研究

Clinical Research of the Therapy of Extracorporeal Shock Wave to Chronic Acalculous Cholecystitis

目的体外冲击波治疗慢性非结石性胆囊炎的疗效观察及临床研究。方法对80例慢性非结石性胆囊炎患者随机分成2组,每组40例;治疗组采用上海交大JDPN-VB型体外冲击波碎石机,以右上腹部为冲击波路径,俯卧位,对病变胆囊进行体外冲击波治疗,每次治疗电压选择8~10 k V,冲击波次数为1 000次,间隔2周治疗下一次,2次为1个疗程;对照组采用消炎利胆药口服4周。两组分别于开始治疗4周后评估慢性非结石性胆囊炎治疗前后临床指标的变化。结果治疗4周后,发现治疗组慢性非结石性胆囊炎的临床症状、胆囊彩超变化等单项指标改善程度及综合疗效均明显优于对照组。结论体外冲击波是治疗慢性非结石性胆囊炎行之有效的新方法,此方法起效快,安全可靠,疗效显著,值得临床推广应用。

Objective This article aims to conduct the clinical observation and clinical research of extracorporeal shock wave therapy to chronic acalculous cholecystitis.Methods Divide 80 cases of patients of chronic acalculous cholecystitis into 2 groups,with 40 cases in each group; as for the treatment group,the JDPN-VB model extracorporeal shock wave lithotripter by Shanghai Jiao Tong University is adopted to take the right upper quadrant as the shock wave path,and in prone position,to conduct the extracorporeal shock wave therapy to the gallbladder with the therapy voltage of 8-10 kv and the times of shock wave of 1000,and with the intervals of 2 weeks between two times; 2 times are taken as 1 course of treatment; as for the control group,the anti-inflammatory and cholagogic medicines are taken for four weeks.Four weeks after the start of therapy,the two groups of patients are evaluated about the changes of clinical index before and after the chronic acalculous cholecystitis.Results After 4 weeks of therapy,it is found that the single index improvement degree and comprehensive therapeutic effect such as the clinical symptoms and the change in gallbladder Color Doppler Ultrasound of the treatment group are all obviously superior to that of the control group.Conclusions The extracorporeal shock wave is a new effective method for the therapy of chronic acalculous cholecystitis; it has the advantages of rapid effectiveness,safe and reliable and with effective therapy; worthy of clinic popularization and application.