曲美他嗪治疗冠心病合并心律失常的效果观察

Study on Trimetazidine Medication Effect in Treatment of Coronary Heart Disease Complicated with Arrhythmias

目的探讨曲美他嗪治疗冠心病合并心律失常的效果观察。方法选取2013年11月到2014年11月我院接诊的43例冠心病合并心率失常患者,随机分为23例实验组和20例对照组,实验组给与曲美他嗪片,对照组给予硝苯地平控释片,观察两组患者的治疗效果。结果实验组患者的心律失常的有效率、缺血性ST-T段的改善情况及左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)、左室射血分数(LVEF)明显优于对照组,差异显著,有统计学意义(P<0.05)。结论曲美他嗪治疗冠心病合并心律失常的效果显著,可以有效提高心律失常的改善率和缺血性ST-T段的改善情况--,缓解冠心病合并心律失常的临床症状,值得临床推广。

Objective Trimetazidine medication effect in treatment of coronary heart disease complicated with arrhythmias is to be studied. Methods Select 43 patients of coronary heart disease complicated with arrhythmias who are treated in hospital from November 2013 to November 2014 and separate them into two groups at random with 23 patients in study group and 20 patients in control group,patients in study group are given trimetazidine medication treatment,while patients in control group are given nifedipine GITS medication treatment; and then observe and compare treatment effects between two groups. Results Patients’treatment efficacy and their ischemic ST-T segment improvement in study group are much better than those in control group;besides,patients’scores of LVEDD,LVESD and LVEF in study group are much more favorable than counterparts in control group;there is a treatment differential between two groups,and such a differential has statistic value（P〈0.05）.Conclusion Trimetazidine medication is of efficacy in treatment of coronary heart disease complicated with arrhythmias;it is conducive to improving patients’treatment efficacy of arrhythmias and promoting their ischemic ST-T segment improvement and relieving il ness symptoms;thus,such a medication treatment is quite worthwhile to be applied.