摘要
目的：研究溃疡性结肠炎应用美沙拉嗪栓剂治疗的临床疗效。方法选取我院2013年4月～2014年4月间收治的36例溃疡性结肠炎患者，对照组接受美沙拉嗪肠溶片口服治疗，治疗组同时接受美沙拉嗪栓剂治疗，比较两组临床疗效。结果治疗组总有效率（92.86%）、黏膜病变缓解率（92.86%）与对照组（81.82%）、（77.27%）相比较高，两组患者临床疗效差异显著，有统计学意义（P〈0.05）。结论溃疡性结肠炎应用美沙拉嗪栓剂治疗能够增加肠道药物浓度，缩短康复进程，预防不良反应，安全性高，值得推广。
Objective Clinical efficacy of mesalamine suppository in treatment of ulcerative colitis is to be investigated. Methods Choose 36 ulcerative colitis patients who are treated in hospital from April 2013 to April 2014,patients in control group are given mesalamine enteric-coated tablets treatment;while patients in study group are given additional mesalamine suppository treatment,and then observe and compare treatment efficacy in these two groups. Results Treatment efficacy（92.86%）and mucosal disease remission rate（92.86%）in study group are higher than counterparts in control group（81.82%）,（77.27%）; there is differential between study group and such a differential has statistic value（P〈0.05）. Conclusion Mesalamine suppository is of efficacy in treatment of ulcerative colitis;it is conducive to increasing intestinal medicine concentration,shortening treatment course and preventing from side effect with safety;therefore,such a treatment method is quite worthwhile to be promoted widespread.
出处
《中国卫生标准管理》
2015年第9期243-244,共2页
China Health Standard Management
