摘要
β-谷甾醇广泛存在于各种植物油、坚果等植物种子中,具有降低胆固醇、消炎解热、抗氧化、抗肿瘤和抗癌等药理作用,在医药、食品、保健品和化妆品等行业广泛应用.近年来,随着对β-谷甾醇结构修饰、生物活性等研究的不断深入,已经合成出系列的β-谷甾醇衍生物.对β-谷甾醇结构改造的研究现状进行了系统综述.
β-sitosterol widely exists in various kinds of vegetable oils, nuts and other plant seeds, has comprehensive pharmacological activities,such as reducing serum cholesterol,anti-inflammatory, antipyretic,antioxidant,antitumor and anti-cancer,and has also extensive use in food,health products and cosmetics industry.In recent years,a great amount of work on the structure modification and biological activities of β-sitosterol has been done intensively. A series of β-sitosterol derivatives were synthesized. Herein, the research reviewed the progress on structure modification of β-sitosterol.
出处
《河南工业大学学报（自然科学版）》
CAS
北大核心
2015年第2期107-112,共6页
Journal of Henan University of Technology：Natural Science Edition
基金
国家自然科学基金项目(21172055
21302042)
河南省教育厅自然科学研究计划项目(12A15007
14B150053)
郑州市科技创新团队项目(131PCXTD605)
关键词
Β-谷甾醇
结构修饰
合成
生物活性
β-sitosterol
structure modification
synthesis
biological activities
