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乳球菌介导的重组球菌疫苗研制现状 被引量：2

The current status of research on recombinant vaccines against cocci using Lactococcus as a delivery vehicle
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摘要 大部分球菌主要引起化脓性炎症,研制疫苗防治该类细菌是当前研究的热点领域之一。乳球菌是一种新型疫苗载体,本文综述了乳球菌介导的肺炎链球菌、化脓链球菌、无乳链球菌和金黄色葡萄球菌等疫苗的构建及其作用机制等方面的研制现状。 Most cocci cause pyogenic inflammation.Recent research has focused on the control those bacteria through the use of vaccines.Lactococcus is a new type of vaccine vehicle.This review summarizes use of Lactococcus to create recombinant vaccines against cocci such as Streptococcus pneumoniae,S.pyogenes,S.agalactiae,and Staphylococcus aureus and its mechanism of action.
作者 李文桂 陈雅棠
机构地区 重庆医科大学附属第一医院传染病寄生虫病研究所
出处 《中国病原生物学杂志》 CSCD 北大核心 2015年第2期188-191,共4页 Journal of Pathogen Biology
基金 国家自然科学基金项目(No.30801052 30671835 30500423和30200239)
关键词 乳球菌 球菌 疫苗 综述 Lactococcus cocci vaccine review
分类号 R378.1 [医药卫生—病原生物学]
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参考文献25

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二级参考文献31

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共引文献8

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二级引证文献5

中国病原生物学杂志
2015年 第2期

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