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GATA6对先天性心脏病的影响及其突变位点的检出

The Detection of GATA6 Mutations for the CHD
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摘要 GATA6属胚胎发育过程中心脏细胞的早期标志之一,是参与人类先天性心脏病发病机制中的主要候选基因之一,它对心脏发育起重要调控作用。通过对CHD患者的GATA6基因进行测序,我们发现CHD患者的GATA6基因有不同位点的突变,这些突变位点的检出有助于先天性心脏病的研究和治疗。 GATA6,a early indicator of myocardial cell development,is currently regarded as a main candidate gene of congenital heart disease（CHD）. In the process of heart development,it plays a important role in the development of heart.We found out different mutations in CHD patients by suquencing the gene of GATA6 and those mutations contribute tothe study and treatment of CHD.
作者 鞠叶兰 王晨虹
机构地区 南方医科大学附属深圳市妇幼保健院
出处 《中国优生与遗传杂志》 2015年第4期1-2,8,共3页 Chinese Journal of Birth Health & Heredity
关键词 GATA6 突变位点 CHD GATA6 Detection of mutations
分类号 R541.1 [医药卫生—心血管疾病]
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参考文献27

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中国优生与遗传杂志
2015年 第4期

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