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MYCN和mi RNAs在神经母细胞瘤中的研究进展 被引量:1

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摘要 MYCN高扩增、高表达出现在约20%的神经母细胞瘤中,并且与肿瘤的恶化和不良预后有关。近年来,已明确在神经母细胞瘤的形成中,MYCN是几种mi RNAs的重要调控因子,同时也证明抑癌mi RNAs抑制了MYCN的表达和神经母细胞瘤的增殖。本文总结了神经母细胞瘤中MYCN和mi RNAs的相互作用,以及它们对神经母细胞瘤发病机制的影响。
出处 《中国优生与遗传杂志》 2015年第4期3-5,共3页 Chinese Journal of Birth Health & Heredity
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