纤溶酶联合阿司匹林治疗急性脑梗死的疗效观察

Analysis of the Clinical Effect of Plasmin Combined with Aspirin in the treatment of Acute Cerebral Infarctions and Its Influence on Blood Rheology

目的观察纤溶酶联合阿司匹林治疗急性脑梗死的临床疗效及对血液流变学的影响。方法选择94例急性脑梗死患者,按照随机数表法分为两组,研究组(47例)给予纤溶酶联合阿司匹林治疗,对照组(47例)给予阿司匹林联合红花注射液治疗,观察临床疗效及治疗前后血液流变学情况。结果研究组治疗的总有效率为91.5%,显著高于对照组的72.3%,统计学有显著性差异(P<0.05)。治疗后,两组患者血液流变学指标均有改善,但研究组改善更明显,统计学有显著性差异(P<0.05)。结论纤溶酶联合阿司匹林治疗急性脑梗死临床疗效确切,能改善血液流变学指标,促进神经功能恢复。

Objective To observe the clinical effect of plasmin combined with aspirin in the treatment of acute cerebral infarctions and its influence on blood rheology. Methods 94 patients with acute cerebral infarction were randomly divided into two groups,with the study group（ 47 cases） being treated by plasmin combined with aspirin and the control group（ 47 cases） being treated by aspirin combined with safflower injection. The clinical effects and the blood rheology situation were given in- depth observation. Results The total effective rate of the study group was 91. 5%,which was statistically significantly higher than that of the control group（ 72. 3%,P〈0. 05）. After treatment,the blood rheology indexes of both groups were improved,but the result of the study group was obviously better than that of the control group. The statistics was significantly different（ P〈0. 05）. Conclusion Plasmin combined with aspirin is effective in the treatment of acute cerebral infarction,which could markedly improve the blood rheology indexes and stimulate nerve functional recovery.