自体血循管在透析治疗中的应用效果观察

Application effect observation of autologous blood circulation tube in dialysis treatment

目的探讨自体血循管在透析治疗中的应用价值。方法选择2013年12月~2014年12月于本院进行维持性血液透析患者140例作为研究对象,采用随机数字表法将所有患者分为试验组与对照组,每组70例,对照组按常规血液透析流程操作,试验组在对新的透析器和管路进行常规预冲后应用患者自体血密闭式循管10~15 min,观察两组患者血液透析过程中首次使用综合征（FUS）发生率,对比治疗前后BUN、SCr、ALB、CO2CP的变化。结果对照组共透析828次,发生FUS者23次（2.78%）,试验组患者透析852次,发生FUS者5次（0.59%）,两组比较差异有统计学意义（P〈0.05）;治疗3个月后,试验组与对照组患者BUN、SCr、ALB、CO2CP比较差异有统计学意义（P〈0.05）。结论自体血循管能有效预防患者血液透析过程中FUS的发生,降低透析患者BUN、SCr水平,提高ALB、CO2CP水平,提高血液透析治疗的安全性,降低患者的医疗费用,值得临床推广应用。

Objective To investigate the application effect of autologous blood circulation tube in dialysis treatment.Methods 140 patients with maintenance hemodialysis in our hospital from December 2013 to December 2014 were selected as research objects and divided into test group and control group according to random number table method,with70 cases in each group.Routine hemodialysis process operation was used in control group,autologous blood closed circulation pipe for 10-15 minutes after conventional pre punching new dialysis tube and pipe was used in test group,rate of first use syndrome（FUS） between two groups was observed,change of BUN,SCr,ALB,CO2 CP before and after treatment between two groups were compared. Results Control group accepted 828 times of dialysis,the occurrence of FUS was 23times（2.78%）,the test group accepted 852 times of dialysis,the occurrence of FUS was 5 times（0.59%）,there was significant difference between two groups（P〈0.05）;After three moths of treatment,BUN,SCr,ALB,CO2 CP had significant difference between two groups（P〈0.05）. Conclusion Autologous blood circulation tube can effectively prevent the occurrence of FUS during the course of hemodialysis,it decrease BUN,SCr level of dialysis patients,improve the level of ALB,CO2 CP and the safety of the hemodialysis as well as reduce medical cost objective,is worthy of application and promotion in clinic.