补骨丸治疗股骨头坏死的临床研究

Clinical research on treatment of femoral head necrosis by Bugu Pills

目的:观察补骨丸治疗股骨头坏死的疗效及影响疗效的相关因素。方法:采用补骨丸治疗股骨头坏死60例,并配合拄拐及康复训练,疗程均为1年。随访中观察治疗前后Harris评分、股骨头坏死保髋疗效评价标准百分法评分的变化。结果:患者治疗后Harris评分显著高于治疗前,差异有统计学意义(P<0.01)。患者治疗后保髋疗效评价标准百分法评分显著高于治疗前,差异有显著性意义(P<0.01)。各ARCO分期组比较方差不齐;在α<0.05水平上各ARCO分期组Harris评分比较,差异有统计学意义(P<0.01)。ARCOⅡ期和Ⅲ、Ⅳ期之间有差异,可以认为,ARCOⅡ期优于Ⅲ、Ⅳ期。结论:补骨丸配合康复训练治疗股骨头坏死疗效肯定,ARCO分期可影响中药治疗股骨头坏死疗效,ARCOⅡ期优于Ⅲ、Ⅳ期。

Objective：To observe the effect on femoral head necrosis and the relevent factors of Bugu Pills. Methods：60 cases with femoral head necrosis were treated by Bugu Pills combined with rehabilitation training and crutches intervention, 1 year as a course. In the following-up, the changes of Harris scores, femoral head necrosis of hip preserving evaluation standard percentage score before and after treatment were observed. Results：Compared the Harris scores before and after treatment, the differences were significant （P〈0.01）, the Harris score was obviously higher than that before treatment. Compared the femoral head necrosis of hip preserving evaluation standard percentage scores, the differences was significant （P〈0.01） after treatment, the hip preserving evaluation standard percentage score was obviously higher than that before treatment. The ARCO staging group homogeneity of variance;in comparison with alpha＆lt;0.05 level of each ARCO stage group, Harris score, the difference was significant （P〈0.01）. There were differences between ARCOⅡandⅢ、Ⅳ, which means ARCO IIwas better than III, IV stages. Conclusion：Bugu Pills combined with rehabilitation training has an effect on femoral head necrosis. The phrases of ARCO can influence the efficacy of Chinese medicines, better for ARCOⅡthanⅢ、Ⅳ.