心血管内科住院患者肾功能状况的观察与分析

Survey on renal function of hospitalized patients in department of cardiovascular internal medicine

目的评估和分析因心血管内科疾病住院患者的肾功能状况。方法连续入选因心血管疾病入院心内科的患者,采集患者相关临床资料及常规血液生化指标,以改良的MDRD公式估测肾小球滤过率(e GFR)水平。结果共入选385例患者,血清肌酐高于正常上限者占15.8%(61例),e GFR≥90 ml/(min·1.73 m2)者占47.0%(181例),e GFR<90 ml/(min·1.73 m2)者占53.0%(204例)。其中,年龄、高血压病、糖尿病、冠心病、高尿酸血症是患者发生肾功能下降的危险因素。结论心血管内科住院患者中,肾功能下降患者的比率较高,仅以血清肌酐为诊断标准可能造成漏诊。

Objective To evaluate the general condition of renal function in hospitalized patients in department of cardiovascular internal medicine. Methods The clinical data of routine blood examinations and serum biochemical parameters were collected and analyzed. glomerular filtration rate（ e GFR） was calculated by modified MDRD formula. Results Serum levels of creatinine of 61 patients（ 15. 8%） were higher than the upper limit of normal range; and e GFR≥90 ml /（ min·1. 73 m2） was 181 patients（ 47. 0%）,e GFR 90 ml/（ min·1. 73 m^2） was 204 patients（ 53. 0%）. Age,hypertension,diabetes mellitus,coronary heart disease and high level of serum uric acid were the independent risk factors for renal dysfunction. Conclusion There are higher percentage of renal insufficiency in hospitalized patients in department of cardiovascular internal medicine. Serum level of creatinine is not a sensitive indicator for detection of the condition of renal dysfunction.