脑微出血与高血压的相关性分析

The correlation analysis between the cerebral microbleeds and hypertension

目的探讨脑微出血与高血压的相关性。材料与方法对524例磁共振受检者进行常规序列(T1WI、T2WI、FLAIR)、DWI及磁敏感加权序列(susceptibility weighted imaging,SWI)扫描。对CMBs进行分区、计数、分级。记录受检者高血压病史和MR扫描前血压值,并按其血压值进行分级。将病例分为CMBs组和无CMBs组,比较患者性别、年龄、患高血压病周期(年)、高血压患病率、高血压级别、平均收缩压、舒张压及CMBs在不同区域的多发程度在组间的差别。分析CMBs严重度分级与年龄、血压分级、收缩压、舒张压的相关性。结果脑微出血组高血压患病率、平均收缩压、平均舒张压均高于无脑微出血组。脑微出血组的平均高血压病史较无脑微出血组长。CMBs不同区域的多发程度有统计学差异。CMBs严重度分级与年龄、收缩压、舒张压及血压分级有相关性。结论脑微出血与高血压有明显的相关性。

Objective：To evaluate the correlation between the cerebral microbleeds and the blood pressure. Materials and Methods：A total of 524 subjects were carried out conventional sequences of T1 weight imaging （T1WI）, T2 weight imaging （T2WI）, FLAIR, DWI and susceptibility weighted imaging （SWI）. The brain regions, number and grades of the CMBs were analyzed. The hypertension history, blood pressure values before MR examination were recorded. The blood pressure level of the subjects were divided into different grades. The subjects were divided into two groups：CMBs group and non CMBs group. Then we compare the differences of gender, age, hypertension period （year）, the prevalence rate of hypertension, high blood pressure level, the average systolic pressure, diastolic pressure and CMBs sites between the two groups.The correlation between CMBs and the age, blood pressure grade, Systolic Bp and Diastolic BP was analyzed. Results：The hypertension prevalence, the average systolic blood pressure and the diastolic blood pressure of CMBs group were higher than those of values in non CMBs group. There is a longer hypertension period in CMBs group compared with non CMBs group. The CMBs distribution of different areas had significant difference. The grades of CMBs were correlated with the age, blood pressure grade, Systolic Bp and Diastolic BP. Conclusions：There was signiifcant correlation between the CMBs and hypertension.