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转鼓式生物反应器中液相体系的流动性能 被引量:1

Flow Properties of Liquid Phase Systems in a Rotating Drum Bioreactor
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摘要 采用粒子示踪测速法在18 L转鼓式生物反应器中考察了转速和挡板数、挡板类型和粘度对转鼓流场的影响.结果表明,在低粘的自来水介质中,转速为4~12 r/min时,Y向平均分速度由0.029 m/s增加到0.053和0.064 m/s时,挡板重力提升能力不断增强,提高转鼓转速可促进全局混合.直挡板数由4增加到8时,挡板提升能力增强32.5%,且能获得更均匀的流场分布;与自来水体系相比,高粘度8 g/L黄原胶溶液体系中流场分布更均匀,剪切更温和. Particle image velocimetry was used to investigate the flow profile of rotating drum bioreactor influenced by rotational speed and lifters with different numbers and configurations in two viscosity systems of tap water (μ=-1mPa.s) and 8 g/L xanthan gum solution (r=-10.97 Pa,μ=1 180 mPa.s). The results showed that for low viscosity water system, mean Yvelocity was increased from 0.029 to 0.053 and 0.064 m/s, and global mixing performance and lifters hoisting capacity was promoted with the rotational speed from 4 to 12 r/min. With the increase of lifter number from 4 to 8, a more uniform flow field was obtained, and lifters hoisting capacity promoted by 32.5%. Compared with tap water, a more uniform flow field with more moderate shear stress formed in high viscosity system of 8 g/L xanthan gum solution.
出处 《过程工程学报》 CAS CSCD 北大核心 2015年第2期190-197,共8页 The Chinese Journal of Process Engineering
基金 国家重点基础研究发展规划(973)基金资助项目(编号:2010CB630904) 国家自然科学基金资助项目(编号:21206166) 国家高技术研究发展计划(863)基金资助项目(编号:2012AA021303)
关键词 转鼓式生物反应器 粒子示踪测速法 挡板 转速 流场 rotating drum bioreactor particle image velocimetry lifter rotational speed flow field
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  • 1Rossi G. The Design of Bioreactors [J]. Hydrometallurgy, 2001, 59(2/3): 217-231.
  • 2Wang S J, Zhong J J. A Novel Centrifugal Impeller Bioreaetor: Fluid Circulation, Mixing, and Liquid Velocity Profiles [J]. Biotechnol. Bioeng., 1996, 51(5): 511-519.
  • 3Li X Y, Yu G Z, Yang C. Experimental Study on Surface Aerators Stirred by Triple Impellers [J]. Ind. Eng. Chem. Res., 2009, 48(18): 8752-8756.
  • 4Zhang Q H, Wang Z H, Wen S M. Gas-Liquid Mass Transfer Characteristics in a Rotating-drmn Bioreactor [J]. Chem. Eng. Teehnol., 2012, 35(10): 1842-1848.
  • 5Papoutsakis C E. Fluid-mechanical Damage of Animal Cells in Bioreactors [J]. Trends. Biotechnol., 1991, 9(1): 427-437.
  • 6Zhong J J, Yu J, Toshida T. Recent Advances in Plant Cell Cultures in Bioreactors [J]. World J. Microbiol. Biotechnol., 1995, 11(4): 461-467.
  • 7于仲海.MD吸附纸鼓式干燥机与普通吸附干燥机经济对比[J].压缩机技术,2006(3):28-30. 被引量:2
  • 8Third J R, Scott D M, Scott S A. Axial Dispersion of Granular Material in Horizontal Rotating Cylinders [J]. Powder Teehnol., 2010, 203(3): 510-517.
  • 9Ahmadian H, Hassanpour A, Ghadiri M. Analysis of Granule Breakage in a Rotary Mixing Drum: Experimental Study and Distinct Element Analysis [J]. Powder Technol., 2011, 210(2): 175-180.
  • 10Kuo H P, Shih P Y, Hsu R C. Coupled Axial-Radial Segregation in Rotating Drums with High Fill Levels [J]. AIChE J., 2006, 52(7): 2422-2427.

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