临床药师对住院医嘱审查中的用药差错因素分析及再评价

Re-evaluation and analysis on medication error factors in inpatient prescriptions review by clinical pharmacist

目的:了解通过临床药师住院医嘱审查发现用药差错的情况及其对患者造成的伤害。方法:采用回顾性分析方法,对2012年9月–2013年8月我院226例住院医嘱审查中临床药师发现的用药差错进行识别和再评价。结果:226例住院医嘱涉及用药差错共141例(62.39%),以抗感染药物的发生率居首位,以C类用药差错为主。用药差错表现居前3位的分别为用法用量错误(39.01%)、遴选药品品种错误(21.27%)、存在配伍禁忌或不良相互作用(15.60%)。经临床药师的沟通交流,医生对67.38%的用药差错采取了相应的调整措施。结论:临床药师在对住院医嘱审查过程中,应加强识别用药差错混杂因素,避免用药差错的发生。

Objective： To understand the occurrence of medication errors in inpatient prescriptions review by clinical pharmacist and its impact on the patients. Methods：Based on retrospective analysis, we identiifed and re-evaluated medication errors from 226 cases of the perspective inpatient prescriptions review by clinical pharmacist in our hospital from September 2012 to August 2013. Results：About 141 cases of medication errors （62.39%） mixed in 226 cases of inpatient prescription review. Anti-infection agents took the leading position. The classiifcations of 141 cases of medication errors mainly belonged to Class C. The top three medication errors were inappropriate usage and dosage （39.01%）, unsuited drug selection （21.27%） and potential drug interaction （15.60%）. After the communication with physicians, 67.38% of medication errors had been adjusted. Conclusion：It is necessary for clinical pharmacist to strengthen the identification factors of medication error during the review of inpatient prescriptions in order to reduce the occurrence of medication errors.