ABO血型与9种恶性肿瘤相关性研究

Research on correlation between ABO blood groups and nine kinds of cancers

目的:研究ABO血型与9种恶性肿瘤发生的危险度关系。方法:收集2013年7月至2014年7月甘肃省肿瘤医院收治的9种恶性肿瘤患者的ABO血型结果。通过对比9种恶性肿瘤患者与甘肃省人群的ABO血型分布情况判断不同肿瘤的发生与ABO血型的相关性;A、B、O、AB 4种血型分别比较恶性肿瘤患者相对于正常对照发生疾病的OR值来确定各血型人群发生9种恶性肿瘤的相对危险度。结果:9种恶性肿瘤中肺癌、胃癌、直肠癌与乳腺癌患者的ABO血型分布情况与正常对照有显著差异性,其中A型人群为高风险人群。结论:肺癌、胃癌、直肠癌与乳腺癌患者中ABO血型构成比与正常人群有差异,A型人群为高风险人群。

Objective：To research the correlation between ABO blood groups and the morbidity risk of nine cancers. Methods：The patients of nine cancers in Gansu provincial cancer hospital during 2013-2014 and healthy people were involved for retrospective analysis of ABO blood type results. The ABO blood groups distribution of nine kinds of cancers and healthy controls was compared to find the correlation between the incidence of cancer and ABO blood groups. Then the OR values of each blood group in nine kinds of cancers were compared with the corresponding blood type in healthy controls to determine the relative of cancers in different ABO blood groups. Results： In nine kinds of cancers, the distribution of ABO blood groups in patients with lung cancer, gastric cancer, colorectal cancer and breast cancer were significantly different with that in healthy controls. Conclusions： In nine kinds of cancers, lung cancer, gastric cancer, colorectal cancer and breast cancer were associated with ABO blood group in which people with A blood group had a higher risk of cancer.