血必净注射液与利巴韦林注射液治疗重症麻疹的临床对比

Clinical Comparison of Xuebijing Injection and Ribavirin Injection in Treatment of Severe Measles

目的对比血必净注射液与利巴韦林注射液治疗重症麻疹的临床效果。方法将我院2009年5月至2014年5月收治的98例重症麻疹患者作为研究对象,按照入院顺序将其分为对照组与观察组各49例。两组患者均给予常规对症治疗,对照组在此基础上给予利巴韦林注射液治疗,观察组给予血必净注射液治疗。记录两组患者的临床症状恢复时间和住院时间,并对比两组患者的临床疗效。结果观察组体温复常时间为(3.19±0.91)d,肺部啰音消失时间为(4.91±1.12)d,喉炎缓解时间为(4.71±0.68)d,心衰纠正时间为(2.31±0.61)d,胸片改善时间(6.32±1.41)d,住院时间为(5.51±2.13)d,均明显短于对照组(P<0.05)。观察组治愈26例,显效18例,好转3例,总有效率为95.92%,明显优于对照组的77.55%(P<0.05)。结论血必净注射液治疗重症麻疹患者疗效显著,可缩短患者的住院时间,强化治疗效果,值得推广。

Objective To compare the clinical effect of xuebijing injection and ribavirin injection in treatment of severe measles. Methods 98 patients with severe measles treated in our hospital from May 2009 to May 2014 were set as research objects and divided into control group and observation group according to the order of admission, with 49 cases in each group. Patients in two groups were given conventional and symptomatic treatment, the control group was given ribavirin injection on this basis, while the observation group was given xuebijing injection. The recovery time of clinical symptoms and time of hospitalization were recorded, the clinical effects between two groups were compared. Results In observation group, the body temperature recovery time was （3.19 ± 0.91） d, the pulmonary rale disappearing time was （4.91±1.12） d, the laryngitis remission time was （4.71±0.68） d, the HF correct time was （2.31±0.61） d, the chest radiograph improved time was （6.32±1.41） d and the hospitalization time was （5.51±2.13） d, shorter than those in control group （P〈0.05）. The total effective rate of observation group was 95.92%, with cure in 26 cases, conspicuous effect in 18 cases and improvement in 3 cases, significantly better than 77.55%of control group （P〈0.05）. Conclusions Xuebijing injection has significant effect in treatment of patients with severe measles, and can shorten the hospitalization time, intensify the treatment effect, which deserves promotion.