Q值引导与标准化准分子激光原位角膜磨镶术术后角膜非球面系数Q值变化的远期观察

Long-Term Observation on Changes of Q Values after Q-Guided Aspheric Ablation and Standard Ablation in LASIK

目的观察Q值引导和标准准分子激光原位角膜磨镶术(laser in situ keratomilieusis,LASIK)术后角膜Q值的远期变化趋势,探讨Q值引导LASIK术对维持角膜非球面状态的有效性。方法回顾分析2008年12月至2013年12月,低中度近视患者80例80只眼,分为Q值引导准分子激光手术(Q-value-guided excimer laser surgery,Q-LASIK)组和标准准分子激光手术(Standard excimer laser surgery,S-LASIK)组,每组患者40例40只眼。所有病例跟踪随访3年和3年以上,观察术后角膜Q值的变化趋势。结果术后1、3、6、12、24和36个月,两组患者术后角膜Q值比较,差异有显著意义(P<0.05)。两组患者术后6个月内的Q值变化明显,两组患者术后的Q值均向负值方向变化;术后6个月,两组患者的角膜Q值均基本稳定。结论 Q-LASIK组与S-LASIK组比较,能更好地维持角膜的非球面特性,疗效稳定。

Objective To observe the long-term developing trend of the corneal Q value after Q-value-guided aspheric ablation and standard LASIK and explore the effectiveness of Q-value-guided LASIK surgery in maintaining the corneal aspherieal state. Methods From December 2008 to December 2013, Altogether 80 cases （80 eyes） of patients with low to moderate myopia that had received Q-value-guided excimer laser surgery （Q-LASIK） and standard excimer laser surgery （S-LASIK） were selected and followed up for three or more years, and the development trend of the corneal Q value was analyzed. Results At Month 1, 3, 6, 12, 24 and 36 after the operation, the two sets of results for repetitive measure analysis of variance were significantly different （P 〈 0.05 ）. Within the 6 months after the operation, the Q values of both groups changed dramatically, the difference between the two groups was significant and the Q values of both groups changed toward the negative end. After Month 6, the Q values of both groups were basically stable. Conclusions Q-LASIK maintains corneal aspherical properties better than S-LASIK and the effect was stable.