摘要
目的:了解本院全胃肠外营养液(TPN)的临床使用情况,并对不合理处方进行统计分析,为提高医院安全用药水平提供参考。方法:采用回顾性调查方式,根据《临床诊疗指南肠外肠内营养学分册(2008版)》、《临床静脉用药调配与使用指南》、《新编药物学(17版)》、《临床营养学》、药品说明书等相关参考资料,对本院2012年6月至2014年6月共2年期间的TPN进行临床使用分析,并对其中不合理处方进行统计分析。结果:第1个年期间TPN总共使用3 613份,第2个年期间TPN总共使用4 357份,其中审查出不合理处方共235份,占总处方的2.95%,其中无适应证用药59例,处方配比不合理124例,处方设计未考虑患者的个体化差异52例。结论:临床在应用TPN时,应针对患者的具体情况,设计合理的处方,药师应充分发挥专业技能,加强对TPN处方的审核与监控,及时发现并纠正不合理处方,从而提高患者用药的安全性和有效性。
Objective:To understand the utilization of total parenteral nutrition (TPN) and analyze unreasonable prescription in our hospital in order to provide references for improving the level of safe drug use.Methods: Using the mode of retrospective review, according to the Clinical Guidelines for the Diagnosis and Treatment of Parenteral and Enteral Nutrition (2008 edition), Clinical Pharmacy Intravenous Admixture and Guidance, Pharmacology (17th Edition), Clinical Nutriology, drug labels and related references, clinical utilization of TPN prescriptions from June 2012 to June 2014 was analyzed, and unreasonable prescriptions were statistically analyzed.Results: There were 3 613 TPN prescriptions in the first year and 4 357 TPN in the second year, among which there were 235 unreasonable prescriptions, accounting for 2.95%. The main problems of unreasonable prescription included: absence of indications (59 cases), improper prescription formula (124 cases), and ignorance of individual difference during formula design (52 cases).Conclusion:The clinical use of TPN should be reasonably designed based on specific conditions, and pharmacist should command special capability to strengthen prescription review and monitoring, discover and correct the unreasonable prescription timely in order to enhance the safety and effectiveness of drug therapy.
出处
《临床药物治疗杂志》
2015年第2期77-80,共4页
Clinical Medication Journal
基金
浙江丽水市科技计划自筹经费项目(2012ZC044)