单纯甲状腺激素治疗对甲减合并阻塞性睡眠呼吸暂停低通气综合征患者睡眠参数的影响

The Impact of the Simple Thyroid Hormone Therapy on The Respiratory Sleep Indicators of Hypothyroidism with Obstructive Sleep Apnea Hypopnea Syndrom

目的:探讨单纯甲状腺激素治疗对甲减合并阻塞性睡眠呼吸暂停低通气综合征呼吸睡眠指标的影响。方法:收集甲减合并阻塞性睡眠呼吸暂停低通气综合征患者49例,给予单纯甲状腺激素治疗4个月,比较治疗前后呼吸睡眠指标的变化。结果:治疗后随着甲状腺功能、体重指数的好转,呼吸睡眠指标也随之好转(P<0.001)。结论:对于部分甲减合并阻塞性睡眠呼吸暂停综合征的患者给予单纯甲状腺激素治疗可改善其睡眠障碍。

Objective： To investigate the impact of the simple thyroid hormone therapy on respiratory sleep indicators of the hypothyroidism with obstructive sleep apnea hypopnea syndrome. Methods： 49 cases of hypothyroidism with obstructive sleep apnea hypopnea syndrome were collected,and treated with simple thyroid hormone for 4months to compare the respiratory sleep indicators before and after treatment. Results： The respiratory sleep indicators has been improved as with the improvement of thyroid function and body mass index after treatment（ P〈0. 001）. Conclusion： The simple thyroid hormone therapy can improve the sleep disorders for the hypothyroidism with obstructive sleep apnea hypopnea syndrome.