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Th17/Treg细胞与HBV感染相关肝病关系的研究进展 被引量:6

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摘要 人体感染乙型肝炎病毒(hepatitis B virus,HBV)后,约10%的成人和90%的儿童转为慢性乙型肝炎或HBV携带者,并可进一步发展为肝硬化和肝细胞癌。近年研究发现,辅助性Th17细胞(T help cell 17,Th17)和调节性T细胞(regulatory T cell,Treg)在分化发育上既相互协调又相互制约,在功能上存在着协同与拮抗的关系,与HBV感染相关肝病的发生发展密切相关。
出处 《实用医学杂志》 CAS 北大核心 2015年第7期1050-1052,共3页 The Journal of Practical Medicine
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  • 1张占卿,张志勇.慢性乙型肝炎的疾病状态评估[J].中华临床医师杂志(电子版),2012,6(20):6-8. 被引量:8
  • 2Thomas F Baumert,Robert Thimme,Fritz von Weizscker.Pathogenesis of hepatitis B virus infection[J].World Journal of Gastroenterology,2007,13(1):82-90. 被引量:50
  • 3Nam JS,Terabe M,Kang MJ,et al.Transforming growth factor β subverts the immune system into directly promoting tumor growth through interleukin-17[J].Cancer Res,2008,68(10):3 915-3 923.
  • 4Hinrichs CS,Kaiser A,Paulos CM,et al.Type 17 CD8+T cells display enhanced anti-tumor immunity[J].Blood,2009,114:596-599.
  • 5Bronte V.Th17 and cancer:friends or foes?[J].Blood,2008,112:214.
  • 6Muranski P,Restifo NP.Does IL-17 promote tumor growth?[J].Blood,2009,114:231-232.
  • 7Nurieva R,Yang XO,Chung Y,et al.Cutting edge:in vitro generated Th17 cells maintain their cytokine expression program in normal but not lymphopenic hosts[J].J Immunol,2009,182:2 565-2 568.
  • 8Lee YK,Turner H,Maynard CL,et al.Late developmental plasticity in the T helper 17 lineage[J].Immunity,2009,30:92-107.
  • 9Dhodapkar KM,Barbuto S,Matthews P,et al.Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myeloma[J].Blood,2008,112:2 878-2 885.
  • 10Yang XO,Nurieva R,Martinez GJ,et al.Molecular antagonism and plasticity of regulatory and inflammatory T cell programs[J].Immunity,2008,29:44-56.

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  • 1Canet E,Dantal J,Blancho G,et al.Tuberculosis following kidney transplantation:clinical features and outcome.A French multicentre experience in the last 20years[J].Nephrol Dial Transplant,2011,26(11):3773-3778.
  • 2Brusselle GG,Joos GF,Bracke KR.New insights into the immunology of chronic obstructive pulmonary disease[J].Lancet,2011,378(9795):1015-1026.
  • 3Mannino DM,Buist AS.Global burden of COPD:risk factors,prevalence,and future trends[J].Lancet,2007,370(9589):765-773.
  • 4da Silva PS,de Aguiar VE,de Carvalho WB,et al.Value of clinical pulmonary infection score in critically ill children as a surrogate for diagnosis of ventilator-associated pneumonia[J].J Crit Care,2014,29(4):545-550.
  • 5Matthaiou DK,Ntani G,Kontogiorgi M,et al.An ESICM systematic review and meta-analysis of procalcitonin-guided antibiotic therapy algorithms in adult critically ill patients[J].Intensive Care Med,2012,38(6):940-949.
  • 6Wang W,Shao S,Jiao Z,et al.The Th17/Treg imbalance and cytokine environment in peripheral blood of patients with rheumatoid arthritis[J].Rheumatol Int,2012,32(4):887-893.
  • 7孙晓飞,施志强,徐庆.Th17/Treg平衡在肝纤维化中的作用[J].中华临床医师杂志(电子版),2012,6(24):8243-8244. 被引量:6
  • 8王伟伟,沈茜.Th17细胞和Treg细胞在人类常见疾病中的表达及相互关系[J].中国免疫学杂志,2010,26(3):284-288. 被引量:20
  • 9殷杰,徐栋花,冯灏.Th17/Treg细胞在慢性乙型肝炎发病机制及临床转归中的作用[J].实用肝脏病杂志,2011,14(5):389-392. 被引量:5
  • 10胡锦辉,毕胜利,吕元.Th17细胞——正逐步获得深入研究[J].中国免疫学杂志,2012,28(4):372-378. 被引量:7

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