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肠道菌群与支气管哮喘关系的研究进展 被引量:7

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摘要 人体肠道内细菌数量巨大,种类繁多,目前已发现500多种,细菌数目约10^14个,为人体细胞总数的10倍,是一个极其庞大及复杂的微生态系统。不同个体肠道细菌成分差异较大,甚至是在双胞胎之间也有不同。而一旦个体肠道内细菌早期定植形成后,肠道内菌群会保持一个稳定状态,通过这种稳态改变与生理学变化的联系,使利用肠道菌群诊断及治疗疾病成为可能。
出处 《中国综合临床》 2015年第5期475-477,共3页 Clinical Medicine of China
基金 吉林省科技发展计划项目(20080444-1)
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  • 1Tumbaugh PJ, Hamady M,Yatsunenko T, et al. A core gutmicrobiome in obese and lean twins [J]. Nature, 2009, 457?7228) :480-484.
  • 2Faith JJ, Guruge JL, Charbonneau M, et al. The long-term stabilityof the human gut microbiota [ J]. Science, 2013,341 ( 6141 ):1237439.
  • 3Harb H,van Tol EA,Heine H,et al. Neonatal supplementation ofprocessed supernatant from Lactobacillus rhamnosus GG improvesallergic airway inflammation in mice later in life [ J]. Clin ExpAllergy,2013,43(3) :353-364.
  • 4Hong HJ,Kim E, Cho D, et al. Differential Suppression of Heat-Killed Lactobacilli Isolated from kimchi, a Korean TraditionalFood, on Airway Hyper-responsiveness in Mice [J]. J ClinImmunol,2010,30( 3) :449-458.
  • 5Sagar S, Vos AP, Morgan ME, et al. The combination ofBifidobacterium breve with non-digestible oligosaccharidessuppresses airway inflammation in a murine model forchronicasthma [J]. Biochim Biophys Acta, 2014, 1842(4) :573-783.
  • 6第三次中国城市儿童哮喘流行病学调查[J].中华儿科杂志,2013,51(10):729-735. 被引量:1013
  • 7Lovasi GS,Quinn JW,Neckerman KM,et al. Children living inareas with more street trees have lower prevalence of asthma [ J] . JEpidemiol Community Health,2008,62 (7) : 647-649.
  • 8Larch6 M,Robinson DS,Kay AB. The role of T lymphocytes in thepathogenesis of asthma [ J ]. J Allergy Clin Immunol,2003,111(3);450-463.
  • 9Ege MJ,Mayer M, Normand AC, et al. Exposure to environmentalmicroorganisms and childhood asthma [ J]. N Engl J Med, 2011,364(8) :701-709.
  • 10Russell SL, Gold MJ, Hartmann M,et al. Early life antibiotic -drivenchanges in microbiota enhance susceptibility to allergic asthma[J]. EMBO Rep,2012,13(5) ; 440-447.

二级参考文献62

  • 1肖玲莉,杨毅.Th1/Th2免疫应答失衡及其影响因素[J].国际儿科学杂志,2006,33(6):399-402. 被引量:26
  • 2黎君友,于燕,郝军,晋桦,许惠君.分光光度法测定血和小肠组织二胺氧化酶活性[J].氨基酸和生物资源,1996,18(4):28-30. 被引量:202
  • 3Kim H,Kwack K,Kim DY,Ji GE.Oral probiotic bacterial administration suppressed allergic responses in an ovalbumin-induced allergy mouse model.FEMS Immunol Med Microbiol 2005; 45:259-267
  • 4Kim H,Lee SY,Ji GE.Timing of bifidobacterium administration influences the development of allergy to ovalbumin in mice.Biotechnol Lett 2005;27:1361-1367
  • 5Jonkers D,Stockbrugger R.Review article:Probiotics in gastrointestinal and liver diseases.Aliment Pharmacol Ther 2007; 26 Suppl 2:133-148
  • 6Adel-patient K,Bernard H,Ah-Leung S,Creminon C,Wal JM.Peanut-and cow's milk-specific IgE,Th2 cells and local anaphylactic reaction are induced in Balb/c mice orally sensitized with cholera toxin.Allergy 2005; 60:658-664
  • 7Mucida D,Park Y,Kim G,Turovskaya O,Scott I,Kronenberg M,Cheroutre H.Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid.Science 2007; 317:256-260
  • 8Kedzierska A,Kaszuba-Zwoinska J,Slodowska-Hajduk Z,Kapinska-Mrowiecka M,Czubak M,Thor P,Wojcik K,Pryjma J.SEB-induced T cell apoptosis in atopic patients--correlation to clinical status and skin colonization by Staphylococcus aureus.Arch Immunol Ther Exp (Warsz) 2005; 53:63-70
  • 9Yang PC,Xing Z,Berin CM,Soderholm JD,Feng BS,Wu L,Yeh C.TIM-4 expressed by mucosal dendritic cells plays a critical role in food antigenspecific Th2 differentiation and intestinal allergy.Gastroenterology 2007; 133:1522-1533
  • 10Bischoff S,Crowe SE.Gastrointestinal food allergy:new insights into pathophysiology and clinical perspectives.Gastroenterology 2005; 128:1089-1113

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