两种镇痛方法在人工流产手术中的临床比较

Clinical comparison of two kinds of analgesic methods used in artificial abortion

目的比较间苯三酚配伍盐酸奥布卡因凝胶与丙泊酚在人工流产中的临床应用。方法将2011年1月至2012年12月在该院行人工流产术患者400例分为间苯三酚组、丙泊酚组,每组200例,间苯三酚组在术前30.00min肌内注射间苯三酚80.00mg,术前4.00min宫颈注入盐酸奥布卡因凝胶30.00mg。丙泊酚组在丙泊酚配合芬太尼静脉全身麻醉下实施手术。观察记录两组对象宫口松弛情况、手术时间、疼痛程度、术中及术后30.00min阴道流血情况、人流综合征发生率、手术费用。结果两组对象手术时间、镇痛效果、人流综合征的发生率比较,差异无统计学意义(P>0.05);而间苯三酚组术中宫口松弛、药品、监护费用及呼吸抑制的发生,与丙泊酚组比较,差异有统计学意义(P<0.01)。结论间苯三酚在人工流产中能达到接近丙泊酚组的镇痛效果,且经济实用,无需麻醉监护,可以在基层医院尤其缺少监护设施的医院应用。

Objective To compare the clinical application of phloroglucinol combined with oxybuprocaine hydrochloride gel and propofol in artificial abortion. Methods Four hundreds cases undergoing artificial abortion in our hospital from January 201t to December 2012 were randomly divided into the phloroglucinol group and the propofol group,200 cases in each group. The phloro- glucinol group was intramuscularly injected by phloroglucinol 80.00 mg at 30.00 min before abortion,and oxybuprocaine hydro- chloride gel 30.00 mg by cervical injection at 4.00 min before operation. The propofol group was performed the operation under the general anesthesia of propofol combined with fentanyl. The cervical relaxation, operative time, pain degree, intraoperative vaginal bleeding,vaginal bleeding at postoperative 30.00 rain and occurrence rate of abortion syndrome were observed and recorded in the 2 groups. Results The operative time,analgesic effect,occurrence rate of abortion syndrome and operation cost had no statistically significant differences between the two groups（P^0.05） ;but the cervical relaxation, dugs,monitoring cost and occurrence of respi- ration suppression had statistically significant differences between the two groups（P〈0.01）. Conclusion Phloroglucinol combined with oxybuprocaine can achieve the analgesic effect close to that of proprofol in artificial abortion,is economic and practical without needing anesthesia monitoring,and can be used in the primary hospital especially the hospitals with lack of monitoring devices.